Partial pressures of oxygen and carbon dioxide, pH, and concentrations of bicarbonate, lactate, and glucose in pleural fluid from horses.

摘要: Samples of pleural fluid from 20 horses with effusive diseases various causes were evaluated; samples 19 used for the study. There differences pH (P = 0.001) and partial pressure oxygen (PO2) between arterial blood nonseptic 0.0491), but there no pH, PO2, carbon dioxide (PCO2), concentrations bicarbonate (HCO3-), lactate, glucose venous fluid. Paired comparisons same horse indicated differences. 0.0001, each) PCO2, HCO3- septic Differences also existed 0.0001), PCO2 0.0003), lactate 0.0051), 0.0001) Difference was not found values PO2 fluid, although 4 contained virtually oxygen. revealed less than 0.05) all values, except those PO2. These alterations suggested functional physical compartmentalization that separated healthy tissue. Compartmentalization microenvironmental factors at site infection should be considered when developing therapeutic strategies disease.