High Prevalence of Esophageal Acid Exposure in Very Low Birth Weight Infants Presenting or Not Bronchopulmonary Dysplasia: A Prospective Cross-Sectional Study

摘要: Background: A high frequency of treatment for gastroesophageal reflux disease is observed in neonates with Bronchopulmonary Dysplasia (BPD). The association between these illnesses controversial. Objective: To determine the prevalence index ≥ 10%, very low birth weight infants, presenting or not BPD, using esophageal pH monitoring. Methods: prospective cross-sectional study was conducted. Thirty-five newborns BPD and 15 underwent distal monitoring during their stay a university hospital neonatal unit. symptoms studied both groups. Results: 10% did differ groups (65.7%) (93.3%); p=0.075. Symptoms attributable to occurred 91.4% 73.3% group BPD. Antireflux introduced 80% subjects 20% patients who were BPD; (p<0.001). Conclusions:There increased mucosal exposure acid infants BDP. are frequent groups; however, clinical progression complicated by less frequent. Nevertheless, associated higher treatment, indication any therapeutic modality must be cautious, laboratory investigation evaluation may contribute reduction number unnecessary treatment.