Six-minute-walk distance predicts waiting list survival in idiopathic pulmonary fibrosis.

作者: David J. Lederer , Selim M. Arcasoy , Jessie S. Wilt , Frank D'Ovidio , Joshua R. Sonett

DOI: 10.1164/RCCM.200604-520OC

关键词: Intensive careLung transplantationRetrospective cohort studyFEV1/FVC ratioMedicineIdiopathic pulmonary fibrosisSurvival rateMortality rateSurgeryInternal medicinePulmonary fibrosis

摘要: Rationale: Functional studies may be useful to predict survival in idiopathic pulmonary fibrosis (IPF). Various cutoffs of 6-min-walk distance (6MWD) have been suggested identify patients at a high risk death.Objectives: To examine the association between 6MWD and with IPF listed for lung transplantation, sensitive specific predicting death 6 mo.Methods: We performed retrospective cohort study 454 classified as having transplantation United Network Organ Sharing June 30, 2004 July 22, 2005.Measurements Main Results: Lower was associated an increased mortality rate (p value linear trend < 0.0001). Patients walk less than 207 m had more fourfold greater those or more, despite adjustment demographics, anthropomorphics, FVC % predicted, hypertension, medical comorbidities (adjusted r...

参考文章(28)
D.J. Lederer, S.M. Arcasoy, J.S. Wilt, H.A. Yegen, F. D’Ovidio, J.R. Sonett, S.M. Kawut, 52: Six minute walk distance (6MWD) predicts waiting list survival in Idiopathic Pulmonary Fibrosis (IPF) Journal of Heart and Lung Transplantation. ,vol. 25, ,(2006) , 10.1016/J.HEALUN.2005.11.054
TALMADGE E. KING, JANET A. TOOZE, MARVIN I. SCHWARZ, KEVIN R. BROWN, REUBEN M. CHERNIACK, Predicting survival in idiopathic pulmonary fibrosis: scoring system and survival model. American Journal of Respiratory and Critical Care Medicine. ,vol. 164, pp. 1171- 1181 ,(2001) , 10.1164/AJRCCM.164.7.2003140
A Kadikar, J Maurer, S Kesten, The six-minute walk test : A guide to assessment for lung transplantation Journal of Heart and Lung Transplantation. ,vol. 16, pp. 313- 319 ,(1997)
David A Lynch, J David Godwin, Sharon Safrin, Karen M Starko, Phil Hormel, Kevin K Brown, Ganesh Raghu, Talmadge E King Jr, Williamson Z Bradford, David A Schwartz, W Richard Webb, None, High-resolution computed tomography in idiopathic pulmonary fibrosis: diagnosis and prognosis. American Journal of Respiratory and Critical Care Medicine. ,vol. 172, pp. 488- 493 ,(2005) , 10.1164/RCCM.200412-1756OC
Jason D. Christie, Leah B. Edwards, Anna Y. Kucheryavaya, Paul Aurora, Fabienne Dobbels, Richard Kirk, Axel O. Rahmel, Josef Stehlik, Marshall I. Hertz, Registry of the International Society for Heart and Lung Transplantation: twenty-second official adult lung and heart-lung transplant report--2005. Journal of Heart and Lung Transplantation. ,vol. 29, pp. 1104- 1118 ,(2005) , 10.1016/J.HEALUN.2010.08.004
Gabriel Thabut, Hervé Mal, Yves Castier, Odile Groussard, Olivier Brugière, Rolana Marrash-Chahla, Guy Lesèche, Michel Fournier, Survival benefit of lung transplantation for patients with idiopathic pulmonary fibrosis. The Journal of Thoracic and Cardiovascular Surgery. ,vol. 126, pp. 469- 475 ,(2003) , 10.1016/S0022-5223(03)00600-7
Steven M. Kawut, Mitchell K. O’Shea, Matthew N. Bartels, Jessie S. Wilt, Joshua R. Sonett, Selim M. Arcasoy, Exercise testing determines survival in patients with diffuse parenchymal lung disease evaluated for lung transplantation Respiratory Medicine. ,vol. 99, pp. 1431- 1439 ,(2005) , 10.1016/J.RMED.2005.03.007
NESRIN MOGULKOC, MARTIN H. BRUTSCHE, PAUL W. BISHOP, S. MELANIE GREAVES, ANDREW W. HORROCKS, JIM J. EGAN, Pulmonary Function in Idiopathic Pulmonary Fibrosis and Referral for Lung Transplantation American Journal of Respiratory and Critical Care Medicine. ,vol. 164, pp. 103- 108 ,(2001) , 10.1164/AJRCCM.164.1.2007077
T.M. Egan, L.E. Bennett, E.R. Garrity, F.L. Grover, W.S. Ring, R.C. Robbins, E. Trulock, D.E. Wood, Predictors of death on the UNOS lung transplant waiting list: results of a multivariate analysis. Journal of Heart and Lung Transplantation. ,vol. 20, pp. 242- ,(2001) , 10.1016/S1053-2498(00)00547-7
Christopher J. Lettieri, Steven D. Nathan, Robert F. Browning, Scott D. Barnett, Shahzad Ahmad, Andrew F. Shorr, The distance-saturation product predicts mortality in idiopathic pulmonary fibrosis. Respiratory Medicine. ,vol. 100, pp. 1734- 1741 ,(2006) , 10.1016/J.RMED.2006.02.004