Two-thumb versus two-finger chest compression during CPR in a swine infant model of cardiac arrest

摘要: Study objective: To test the hypothesis that two-thumb chest compression generates higher arterial and coronary perfusion pressures than current American Heart Association-approved two-finger method. Design: Randomized, crossover experimental trial. Setting participants: Animal laboratory experiment with seven swine of either sex weighing 9.4 kg (SD, 0.8 kg), representing infants less 1 year old. Interventions: Animals were sedated IM ketamine/xylazine, intubated a 6.0 Hi-Lo endotracheal tube, anesthetized α-chloralose, paralyzed pancuronium. ECG was monitored continuously. Left femoral Swan-Ganz catheters placed. Cardiac arrest induced an IV bolus KCl verified by pressure tracings. Five Association-certified basic rescuers randomly assigned to perform external compressions for one minute currently recommended method or thorax-squeeze After all five completed their first trial, crossed over other second compressions. Ventilation performed bag-valve device, no drugs given during CPR. three complete cycles, fourth through sixth cycles recorded. Every analyzed systolic, diastolic, mean, pressures. One thousand fifty repeated-measures analysis variance Scheffe multiple comparisons. Results: Systolic blood pressure, diastolic mean significantly ( P Conclusion: The in this infant model cardiac arrest.