Absorption of glucose, amino acids, and dipeptides by the intestines of Atlantic salmon (Salmo salar L.).

作者: A.M. Bakke-McKellep , S. Nordrum , Å Krogdahl , R.K. Buddington

DOI: 10.1023/A:1007872929847

关键词: Absorption (pharmacology)SalmoBrush borderHydrolysisDipeptide transportDipeptideAmino acidBiologyBiochemistryChromatographyProline

摘要: Rates of glucose, amino acid and dipeptide absorption by the intestine Atlantic salmon (Salmo salar L.) were measured in vitro at 10 °C as functions concentration region using intact tissues (everted sleeve method). Salmon (weight range 300–1300 g) fed a commercial, extruded feed, kept 12–13 freshwater. Maximum rates (Vmax) glucose transport low compared to most Vmax values. There was declining proximal-to-distal gradient along post-gastric intestinal tract. A saturable component not evident for proline glycyl-proline distal intestine, glycyl-sarcosine any region. `Apparent diffusion', which may include affinity, high capacity carrier systems carrier-independent influx, appears account majority total uptake higher concentrations acids dipeptides. competition between dipeptides transporter sites pyloric ceca mid suggesting common carrier. also indication hydrolysis these brush border membrane enzymes.

参考文章(33)
R. K. Buddington, J. W. Chen, J. M. Diamond, Dietary regulation of intestinal brush-border sugar and amino acid transport in carnivores. American Journal of Physiology-regulatory Integrative and Comparative Physiology. ,vol. 261, ,(1991) , 10.1152/AJPREGU.1991.261.4.R793
R K Buddington, A M Bakke-Mckellep, A Krogdahl, The intestines of carnivorous fish: structure and functions and the relations with diet Acta Physiologica Scandinavica. ,vol. 638, pp. 67- 80 ,(1997)
Nathan L. Collie, Ronaldo P. Ferraris, Chapter 9 Nutrient fluxes and regulation in fish intestine Biochemistry and Molecular Biology of Fishes. ,vol. 4, pp. 221- 239 ,(1995) , 10.1016/S1873-0140(06)80012-3
R. K. Buddington, J. M. Diamond, Pyloric ceca of fish: a "new" absorptive organ. American Journal of Physiology-gastrointestinal and Liver Physiology. ,vol. 252, ,(1987) , 10.1152/AJPGI.1987.252.1.G65
H N Christensen, Role of amino acid transport and countertransport in nutrition and metabolism. Physiological Reviews. ,vol. 70, pp. 43- 77 ,(1990) , 10.1152/PHYSREV.1990.70.1.43
Ronaldo P. Ferraris, Jared M. Diamond, A method for measuring apical glucose transporter site density in intact intestinal mucosa by means of phlorizin binding. The Journal of Membrane Biology. ,vol. 94, pp. 65- 75 ,(1986) , 10.1007/BF01901014
J.R. Stark, R. Munilla-Morán, Metabolism in marine flatfish—VI. Effect of nutritional state on digestion in turbot, Scophthalmus maximus (L.) Comparative Biochemistry and Physiology B. ,vol. 95, pp. 625- 634 ,(1990) , 10.1016/0305-0491(90)90032-O
Ronaldo P. Ferraris, Gregory A. Ahearn, Intestinal glucose transport in carnivorous and herbivorous marine fishes Journal of Comparative Physiology B-biochemical Systemic and Environmental Physiology. ,vol. 152, pp. 79- 90 ,(1983) , 10.1007/BF00689731
L. J. Schep, I. G. Tucker, G. Young, A. G. Butt, Regional permeability differences between the proximal and distal portions of the isolated salmonid posterior intestine Journal of Comparative Physiology B-biochemical Systemic and Environmental Physiology. ,vol. 167, pp. 370- 377 ,(1997) , 10.1007/S003600050086
William H. Karasov, Jared M. Diamond, A simple method for measuring intestinal solute uptake in vitro Journal of Comparative Physiology A-neuroethology Sensory Neural and Behavioral Physiology. ,vol. 152, pp. 105- 116 ,(1983) , 10.1007/BF00689734