Ethnic-affiliation estimation by use of population-specific DNA markers.

摘要: During the past 10 years, DNA analysis has revolutionized determination of identity in a forensic context. Statements about biological two human samples now can be made with complete confidence. Although markers are very powerful for distinguishing among individuals, most offer little power to distinguish ethnicity or support any statement physical characteristics an individual. Through search literature and unpublished data on allele frequencies we have identified panel population-specific genetic that enable robust ethnic-affiliation estimation major U.S. resident populations. In this report, identify these loci present their levels allele-frequency differential between ethnically defined samples, demonstrate, using log-likelihood analysis, provides significant statistical estimation. addition use estimation, useful both population- individual-level admixture mapping genes by linkage disequilibrium created when populations hybridize.