Efficacy and safety of pharmacotherapy in cancer-related psychiatric disorders across the trajectory of cancer care: a review.

作者: Luigi Grassi , Rosangela Caruso , Karen Hammelef , Maria Giulia Nanni , Michelle Riba

DOI: 10.3109/09540261.2013.842542

关键词: NauseaPalliative careDeliriumAdjustment disordersPharmacotherapyPsychiatryDepression (differential diagnoses)MedicineCancerAnxiety

摘要: AbstractAt least 25–30% of patients with cancer and an even higher percentage in advanced phase illness meet the criteria for a psychiatric diagnosis, including depression, anxiety, stress-related syndromes, adjustment disorders, sleep disorders delirium. A number studies have accumulated over last 35 years on use psychotropic drugs as pillar treatment disorders. Major advances psycho-oncology research also shown efficacy adjuvant cancer-related symptoms, such pain, hot flushes, pruritus, nausea vomiting, fatigue, cognitive impairment. The knowledge about pharmacokinetics pharmacodynamics, clinical use, safety, side effects care is essential integrated multidimensional approach to treated different settings, community-based centres, oncology, palliative care. search major databases (MEDLINE, E...

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