Control of antimicrobial resistance in the health care system.

作者: John E. McGowan , Fred C. Tenover

DOI: 10.1016/S0891-5520(05)70357-3

关键词: Ambulatory careIntensive care medicineNursing homesIntensive careResistant bacteriaInfection controlAntibiotic resistanceMedicineHealth careAntimicrobial

摘要: The frequency with which antimicrobial-resistant microorganisms are recovered from patients in health care settings, such as hospitals and nursing homes, is of great concern to those who manage work systems. 63 Such organisms have become increasingly frequent because the presence more impaired host defenses, use new instrumentation procedures, decreasing resources for infection control, inability some laboratory methods detect novel resistance mechanisms. 41 Strains that been consistently susceptible all antimicrobial agents decades now developed classic therapies. Other recent antimicrobials almost soon drugs marketed. 13 Organisms resistant several different groups also increased during past few years. 62 These multidrug-resistant (MDR) microbes cause an increasing number infections each year. formerly were seen primarily intensive units (ICUs) but occur other inpatient settings even ambulatory care. 1 In cases, MDR strains so prominent keeping serious alive has a difficult task, just preantibiotic era. 24 As magnitude this problem continues broaden, it imperative professionals familiar causes antibiotic ways emergence bacteria can be prevented or minimized. This article highlights factors leading development found various parts system problems control prevention spread these settings.

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