作者: Sacchini , Galimberti , Costa A , Intra M , Luini A
DOI:
关键词: Quadrantectomy 、 Axillary Dissection 、 Clinical trial 、 Early breast cancer 、 Breast cancer 、 Radiation therapy 、 Conservative treatment 、 Cancer 、 Surgery 、 Medicine
摘要: Abstract A little more than 100 years ago Halsted pioneered a surgical approach that led, for the first time, to cure of breast cancer in some patients. Veronesi's contribution was offer same possibility while considerably reducing mutilation went with cure. This article reviews development conservative and synoptically presents results large-scale clinical trials conducted by group Milan 1970s 1980s demonstrate efficacy quadrantectomy, radiotherapy axillary dissection (QUART) as treatment small size cancer. These studies set motion world-wide trend surgery all forms The goes on describe procedures quadrantectomy complete developed Veronesi, outlines new indications for, developments this established technique.