A randomized comparison of sentinel-node biopsy with routine axillary dissection in breast cancer.

摘要: Background Although numerous studies have shown that the status of sentinel node is an accurate predictor axillary nodes in breast cancer, efficacy and safety sentinel-node biopsy require validation. Methods From March 1998 to December 1999, we randomly assigned 516 patients with primary cancer whom tumor was less than or equal 2 cm diameter either total dissection (the axillary-dissection group) followed by only if contained metastases group). Results The number found same two groups. A positive 83 257 group (32.3 percent), 92 259 (35.5 percent). In group, overall accuracy 96.9 percent, sensitivity 91.2 specifi...