Metabolic transformation has a profound effect on anti-inflammatory activity of flavonoids such as quercetin: Lack of association between antioxidant and lipoxygenase inhibitory activity

作者: Wai Mun Loke , Julie M. Proudfoot , Scott Stewart , Allan J. McKinley , Paul W. Needs

DOI: 10.1016/J.BCP.2007.11.002

关键词: Leukotriene B4QuercetinChemistryLipoxygenaseBiological activityFlavonoidMetaboliteBiochemistryEicosanoid ProductionAntioxidant

摘要: … Inflammation and leukocyte recruitment are considered to play key roles in atherogenesis [11]. Inflammatory processes in the vascular wall … Quercetin and 3′-O-methylquercetin were …

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