Unfolded protein response to autophagy as a promising druggable target for anticancer therapy
作者： Dong Hoon Suh , Mi‐Kyung Kim , Hee Seung Kim , Hyun Hoon Chung , Yong Sang Song
DOI: 10.1111/J.1749-6632.2012.06739.X
关键词: Anticarcinogenic Agents 、 Unfolded protein response 、 Biology 、 Cell biology 、 Autophagy 、 Endoplasmic reticulum 、 Signal transduction 、 Cancer cell 、 Apoptosis 、 Druggability
摘要: … , which suppresses general cap-dependent mRNA translation, with the exception of ATF4 mRNA. ATF4 translocates to the nucleus and induces the transcription of genes for amino acid …
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