Bacterial effects and protein corona evaluations: crucial ignored factors in the prediction of bio-efficacy of various forms of silver nanoparticles.

摘要: Because of their unique properties which are strongly dependent on the physicochemical metal nanomaterials, noble nanostructures, particularly silver, have attracted much attention in fields electronics, chemistry, physics, biology, and medicine. Regarding biology medical applications, silver nanoparticles (NPs) recognized as a promising candidate to fight against resistant pathogens because significant antimicrobial activities. However, there two major ignored issues with these NPs. First, effect various types bacteria antibacterial efficacy NPs is ignored; second, no information pattern compositions both soft- hard-corona proteins at surface NPs, can define cellular responses In this article, bacterial capability geometries (i.e., sphere, wire, cube, triangle) was probed; case, three different i...