Mutation analysis of 24 known cancer genes in the NCI-60 cell line set

作者: Ogechi N Ikediobi , Helen Davies , Graham Bignell , Sarah Edkins , Claire Stevens

DOI: 10.1158/1535-7163.MCT-06-0433

关键词: Sequence analysisCancerMutationHRASNeuroblastoma RAS viral oncogene homologGeneticsCarcinogenesisPTENKRASBiologyCancer researchOncology

摘要: … Recently, an ERBB2 Gly 776 mutant non–small cell lung cancer … ERBB2 kinase inhibitor (31), and there has been a report of clinical response to trastuzumab in a patient with ERBB2 …

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