Results from pooled Phase III studies of ulipristal acetate for emergency contraception

摘要: Abstract Background Ulipristal acetate (UPA) is a new effective option to prevent unintended pregnancies up 5 days after unprotected intercourse. We used pooled data from two Phase III studies refine our understanding of the efficacy UPA by time intercourse and effects other factors on pregnancy rates. Study Design Data were create larger analysis population. Analyses performed first participation 2183 women. Results A total 41 women became pregnant despite use UPA, yielding an overall proportion 1.9% (1.3%–2.5%). Proportions higher among those with further acts in same cycle obese These varied 1.3% (0.9%–2.0%) nonobese who had no (n= 1704) 8.3% (0.2%–38.5%) subsequent (n= 12). Conclusions safe preventing Its effectiveness lower have