Diversity of rotavirus serotypes in Mexican infants with gastroenteritis.

摘要: One hundred thirty-two stool specimens from infants with rotavirus gastroenteritis hospitalized in two Mexican cities (Mexico City and Merida) were examined by serotype- subgroup-specific enzyme immunoassays. Among them, 38 (29%) serotype 1, 15 (11%) 2, 13 (10%) 3, 22 (17%) 4, none was 5 or 6, 44 (33%) could not be serotyped. By subgrouping, 121 characterized as follows: 24 (18%) subgroup 97 (74%) had both specificities. While 1 predominated the Mexico area for 4 consecutive years (1984 to 1987), Merida during single epidemic season studied (1985). These data demonstrate that all four primary human serotypes circulated Mexico, being most prevalent. The seroneutralization responses of 14 patients infected strains been previously studied. Of these infants, 11 appeared have infections, indicated absence neutralizing antibodies acute-phase sera their young age (8 months on average) at time illness. Seven seroresponded 4; three 1; low-level seroresponses 3 4. indicate heterotypic antibody occur frequently following infection rotaviruses.