Modular platform for low-light microscopy

摘要: Cell imaging using low-light techniques such as bioluminescence, radioluminescence, and low-excitation fluorescence has received increased attention, particularly due to broad commercialization of highly sensitive detectors. However, the dim signals are still regarded difficult image conventional microscopes, where only microscope in market is primarily optimized for bioluminescence imaging. Here, we developed a novel modular that cost-effective suitable different luminescence modes. Results show this system features excellent aberration correction capabilities enhanced resolution, radioluminescence epifluorescence images were captured compared with commercial microscope.