Chromatographic hydrophobic parameters in correlation analysis of structure-activity relationships.
作者： Eric Tomlinson
DOI: 10.1016/S0021-9673(00)88797-X
关键词: Structure (category theory) 、 Quantitative structure 、 Correlation analysis 、 Chemistry 、 Chromatography
摘要: Abstract The use of RM and ΔRM parameters as indices hydrophobicity for inclusion in quantitative structure activity relationships has been studied. relationship between these other free-energy related is illustrated theoretically experimentally. It suggested that the chromatographically obtained could find a wider applicability structure-activity relationships, their would result improved correlation data.
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