Sfrp5 Modulates Both Wnt and BMP Signaling and Regulates Gastrointestinal Organogensis in the Zebrafish, Danio rerio

作者: Carsten Stuckenholz , Lili Lu , Prakash C. Thakur , Tae-Young Choi , Donghun Shin

DOI: 10.1371/JOURNAL.PONE.0062470

关键词: Liver cellEndodermZebrafishFrizzledMolecular biologyWnt signaling pathwayCell biologyConvergent extensionDanioChordinBiologyGeneral Biochemistry, Genetics and Molecular BiologyGeneral Agricultural and Biological SciencesGeneral Medicine

摘要: … Sfrp5, the focus of this paper, has been shown to bind to the non-canonical Wnt molecules Wnt5a and Wnt11, to inhibit both canonical and non-canonical Wnt signaling in Xenopus …

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