Drug interactions in transplant patients: what everyone should know.

作者: Wana Manitpisitkul , Erin McCann , Sabrina Lee , Matthew R Weir

DOI: 10.1097/MNH.0B013E32832EDCB2

关键词: Therapeutic indexDrugIntensive care medicineTransplant patientMedicine

摘要: Purpose of reviewAdverse events due to drug–drug interactions remain a challenge in the postsurgical care transplant recipients. A combination potent and selective immunosuppressive drugs, which have narrow therapeutic index, with medications for treatment comorbidities such as dyslip

参考文章(107)
Y Vanrenterghem, H Ekberg, J Grinyo, G Tufveson, C Groth, D Cantarovich, L Mjornstedt, S Sadek, R Pichlmayr, F Moreso, G Gannedahl, P Lang, Adam Tegzess, J Rodicio, van Willem Son, A Morgan, A Tarantino, J Peeters, M Campise, J Lodge, K Hutchinson, J Erhard, K Wagner, L Hooftman, S Carl, G Ligtenberg, G Thiel, R Luck, M Wiesel, M Zeiler, Hh Neumayer, Sa Sadek, Jp Soulillou, K Rigg, B Bourgeon, P Fauchald, Hauser, C Brattstrom, R Hene, M Behrend, D Albrechtsen, N Persson, J Morales, PLACEBO-CONTROLLED STUDY OF MYCOPHENOLATE MOFETIL COMBINED WITH CYCLOSPORINE AND CORTICOSTEROIDS FOR PREVENTION OF ACUTE REJECTION The Lancet. ,vol. 345, pp. 1321- 1325 ,(1995)
Kushari Bowalgaha, John O. Miners, The glucuronidation of mycophenolic acid by human liver, kidney and jejunum microsomes British Journal of Clinical Pharmacology. ,vol. 52, pp. 605- 609 ,(2001) , 10.1046/J.0306-5251.2001.01487.X
P E Nolan, J C Wild, S M Butman, PROSPECTIVE STUDY OF THE SAFETY AND FINANCIAL BENEFIT OF KETOCONAZOLE AS ADJUNCTIVE THERAPY TO CYCLOSPORINE AFTER HEART TRANSPLANTATION Journal of Heart and Lung Transplantation. ,vol. 10, pp. 351- 358 ,(1991)
Kenneth S. Lown, Steven A. Wrighton, Paul B. Watkins, Kenneth E. Thummel, Robert J. Fontana, David G. Bailey, Stephen D. Hall, Stephen D. Hall, Leslie Z. Benet, Mary F. Paine, Robert R. Mayo, D. Kim Turgeon, Molecular and physical mechanisms of first-pass extraction. Drug Metabolism and Disposition. ,vol. 27, pp. 161- 166 ,(1999)