Morphology and proliferation of B16 melanoma cells in the presence of lanthanoid and Al3+ ions.
作者： Toshinori Sato , Mineo Hashizume , Yasunobu Hotta , Yoshio Okahata
关键词: Cell division 、 Elongation 、 Lanthanide 、 Ion 、 Nuclear chemistry 、 Inorganic chemistry 、 Melanoma 、 Metal ions in aqueous solution 、 Chemistry 、 Kinetics 、 Morphology (linguistics)
摘要: The effects of trivalent metal ions such as lanthanoid (La , Ce, Nd Sm Gd Er Yb Lu ) and Al on the morphological change proliferation B16 melanoma cells in culture are discussed. These induced transformations decreased growth rates at doses 1 mM. treated with La Ce showed polyhedrical spreading. Elongation axones was dependent ions. a long slender shape. Growth presence mM were significantly lower than that control cells. Measurements cell cycle indicated arrested transitions from G /G to S state. © Rapid Science 1998
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