Role of Cytochrome P450 2C8 in Drug Metabolism and Interactions
作者： Janne T. Backman , Anne M. Filppula , Mikko Niemi , Pertti J. Neuvonen
关键词: Pharmacology 、 Drug 、 Cytochrome P450 、 Repaglinide 、 Pharmacogenetics 、 Gemfibrozil 、 CYP2C8 、 Chemistry 、 Cytochrome P-450 CYP2C8 、 Drug metabolism
摘要: … inhibitors, suggesting that an interplay between CYP2C8 and glucuronides is common. Lack of fully selective and safe probe substrates, inhibitors… on substrates, inhibitors, inducers, and …
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