Rapid determination of enzyme activities of recombinant human cytochromes P450, human liver microsomes and hepatocytes.
作者： Anima Ghosal , Neil Hapangama , Yuan Yuan , Xiaowen Lu , Debra Horne
DOI: 10.1002/BDD.374
关键词: Drug metabolism 、 Biochemistry 、 Cytochrome P450 、 CYP2B6 、 CYP2A6 、 CYP1A2 、 Plate reader 、 Microsome 、 CYP3A4 、 Biology
摘要: … The inhibition and correlation data indicate that the following substrates can be used confidently to determine P450 activities in human liver microsomes: 7-ER and CEC for CYP1A2, …
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