Mechanically-amplified plasma processing for drug engineering
作者： Masayuki Kuzuya , Yasushi Sasai , Motoaki Mouri , Shin-ichi Kondo
DOI: 10.1016/S0040-6090(02)00029-9
关键词: Plasma processing 、 Low-density polyethylene 、 Dangling bond 、 Radical 、 Polyethylene 、 Drug carrier 、 Chemical engineering 、 Polymer chemistry 、 High-density polyethylene 、 Kinetics 、 Chemistry
摘要: We report here special features of mechanochemical reaction plasma-irradiated polyethylene (PE), low density PE (LDPE) and high (HDPE). A dangling bond site (DBS) three component radicals formed on a surface by argon plasma-irradiation disappears rapidly mechanical vibration with Teflon twin-shell blender, causing successively solid state radical recombination reaction. When is similarly conducted together powdered drug, the sustained release powders are obtained due to trapping drugs into powder matrix plasma-induced radicals.
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