Skeletal muscle energetics are compromised only during high-intensity contractions in the Goto-Kakizaki rat model of type 2 diabetes.

作者: Matthew T. Lewis , Jonathan D. Kasper , Jason N. Bazil , Jefferson C. Frisbee , Robert W. Wiseman

DOI: 10.1152/AJPREGU.00127.2019

关键词: MitochondrionSkeletal muscleEndocrinologyChemistryOxidative phosphorylationHigh intensityInsulin resistanceEnergeticsType 2 diabetesRat modelInternal medicine

摘要: Type 2 diabetes (T2D) presents with hyperglycemia and insulin resistance, affecting over 30 million people in the United States alone. Previous work has hypothesized that mitochondria are dysfuncti...

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