Association of the metabolic syndrome with early coronary disease in families with frequent myocardial infarction.

作者: Wibke Reinhard , Stephan R. Holmer , Marcus Fischer , Christian Gloeckner , Ute Hubauer

DOI: 10.1016/J.AMJCARD.2005.10.063

关键词: CardiologyMyocardial infarctionProspective cohort studyCoronary artery diseaseCirculatory systemRisk assessmentMetabolic syndromeMedicineInternal medicineProportional hazards modelDiabetes mellitus

摘要: This study examined the extent to which metabolic syndrome (MS) augments risk for major cardiovascular events in healthy patients with a strong genetic background coronary artery disease (CAD). In prospective cohort study, we 1,316 without previously diagnosed CAD or diabetes mellitus. Patients were participants of Regensburg Myocardial Infarction Family Study, ≥2 family members had severe and 1 myocardial infarction (MI) at

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