The Permeability of the Blood-Brain Barrier in Acute Hypertension. Comparison of an Endogenous and Exogenous Protein Tracer

作者: H. J. Houthoff , K. G. Go , I. Molenaar

DOI: 10.1007/978-3-642-81553-9_4

关键词: Permeability (electromagnetism)MedicineExogenous proteinBlood–brain barrierEndocrinologyFixation (histology)Internal medicinePerfusionMetaraminolEndogenySystemic blood pressure

摘要: Experimental acute hypertension in male Wistar rats was produced by metaraminol infusion to systemic blood pressure levels of 190–210 mm Hg. After 20 sec or 30 min the animals were killed perfusion fixation with 8% formaldehyde perfusion.

参考文章(8)
M J Hernández, R W Brennan, G S Bowman, Cerebral blood flow autoregulation in the rat. Stroke. ,vol. 9, pp. 150- 154 ,(1978) , 10.1161/01.STR.9.2.150
E. Westergaard, B. van Deurs, H. E. Brøndsted, Increased vesicular transfer of horseradish peroxidase across cerebral endothelium, evoked by acute hypertension Acta Neuropathologica. ,vol. 37, pp. 141- 152 ,(1977) , 10.1007/BF00692060
Z. Nagy, G. Mathieson, I. H�ttner, Blood-brain barrier opening to horseradish peroxidase in acute arterial hypertension Acta Neuropathologica. ,vol. 48, pp. 45- 53 ,(1979) , 10.1007/BF00691790
Stavros J. Baloyannis, Nicholas K. Gonatas, Distribution of anti-HRP antibodies in the central nervous system of immunized rats after disruption of the blood brain barrier. Journal of Neuropathology and Experimental Neurology. ,vol. 38, pp. 519- 531 ,(1979) , 10.1097/00005072-197909000-00006
S. Nag, D. M. Robertson, H. B. Dinsdale, Quantitative estimate of pinocytosis in experimental acute hypertension Acta Neuropathologica. ,vol. 46, pp. 107- 116 ,(1979) , 10.1007/BF00684811
RAMZI S. COTRAN, MORRIS J. KARNOVSKY, ANDRES GOTH, RESISTANCE OF WISTAR/FURTH RATS TO THE MAST CELL-DAMAGING EFFECT OF HORSERADISH PEROXIDASE Journal of Histochemistry and Cytochemistry. ,vol. 16, pp. 382- 383 ,(1968) , 10.1177/16.5.382
H J Houthoff, K G Go, Endogenous versus exogenous protein tracer passage in blood-brain barrier damage Advances in Neurology. ,vol. 28, pp. 75- 81 ,(1980)