Multiple-capillary measurement of RBC speed, flux, and density with optical coherence tomography

作者: Jonghwan Lee , Weicheng Wu , Frederic Lesage , David A Boas

DOI: 10.1038/JCBFM.2013.158

关键词: Capillary actionMicroscopyMicrovascular flowOpticsOptical imagingMaterials scienceOptical coherence tomographyFluxPathologyLinear densityRats sprague dawley

摘要: As capillaries exhibit heterogeneous and fluctuating dynamics even during baseline, a technique measuring red blood cell (RBC) speed flux over many at the same time is needed. Here, we report that optical coherence tomography can capture individual RBC passage simultaneously located different depths. Further, demonstrate ability to quantify speed, flux, linear density. This will provide means monitor microvascular flow depths time.

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