Anchoring villi in human placental basal plate: lymphocytes, macrophages and coagulation.

作者: Carlos A. Labarrere , W.Page Faulk

DOI: 10.1016/0143-4004(91)90021-7

关键词: Major histocompatibility complexImmunologyAntibodyBiologyImmune systemPlacentaFibrinMacrophageBasal plate (neural tube)Tissue factorCell biology

摘要: Abstract We have studied basal plates in 25 normal placentae, ten placentae from primary aborters and six secondary for leukocyte markers coagulation components. Anchoring villi contained class II MHC antigen-reactive (HLA-DR, DP DQ) macrophages T-lymphocytes of the helper (CD4) phenotype. Antibodies to components revealed presence tissue factor, factor IX fibrin around anchoring villi. Immune cells were more frequently identified aborters. These findings provide morphological support an idea that there is a linkage between immune plate. Helper can activate which release cytokines through extrinsicpathway. envision this as expression maternal allogeneic recognition extraembryonic tissues

参考文章(39)
J N Bulmer, P M Johnson, Macrophage populations in the human placenta and amniochorion. Clinical and Experimental Immunology. ,vol. 57, pp. 393- 403 ,(1984)
C W Redman, L Sutton, D Y Mason, HLA-DR positive cells in the human placenta. Immunology. ,vol. 49, pp. 103- ,(1983)
Y Nemerson, Tissue factor and hemostasis Blood. ,vol. 71, pp. 1- 8 ,(1988) , 10.1182/BLOOD.V71.1.1.BLOODJOURNAL7111
BAE-LI HSI, CHANG-JING G. YHE, Monoclonal antibody GB25 recognizes human villous trophoblasts. American journal of reproductive immunology and microbiology : AJRIM. ,vol. 12, pp. 1- 3 ,(1986) , 10.1111/J.1600-0897.1986.TB00049.X
W. Page Faulk, W. Hijmans, Recent developments in immunofluorescence. Progress in allergy. ,vol. 16, pp. 9- 39 ,(1972) , 10.1159/000393067
A K Bhan, S E Kabawat, M Mostoufi-Zadeh, S G Driscoll, Implantation site in normal pregnancy. A study with monoclonal antibodies. American Journal of Pathology. ,vol. 118, pp. 76- 84 ,(1985)
Michael Wells, Bae-Li Hsi, W. Page Faulk, Class I antigens of the major histocompatibility complex on cytotrophoblast of the human placental basal plate. American Journal of Reproductive Immunology. ,vol. 6, pp. 167- 174 ,(1984) , 10.1111/J.1600-0897.1984.TB00132.X