Fetal Cell Reprogramming and Transformation

摘要: The fetal cells in primordial organs have the ability to make terminally differentiated within context of embryonic development and organogenesis. Recent advances stem cell field confirm reprogramming capacity transform into different same or other lineages under specific cellular environments called ‘niche.’ In particular, existing show multipotent pluripotent properties, which further emphasizes importance these regenerative medicine tissue engineering both humans animals. Reprogramming involves manipulations genetic configuration changes acellular microenvironments. While this technology is widely used establish transplantable reprogrammed their derivatives regenerate replace damaged tissues, careful considerations should be made terms plasticity as well anticipated ethical issues. chapter, general concepts subsequent phenotypic transformation are reviewed understand aspects plasticity. Potential feasibility manipulation with consideration issues has been described subsequently.