Value of Soluble Markers in the Diagnosis of Reperfusion after Thrombolysis

作者: Fred S. Apple

DOI: 10.1007/978-94-017-2380-0_13

关键词: Myocardial infarctionChest painInternal medicineMedicineCreatine kinaseEcg leadCardiologyThrombolysisPain onsetST segmentTherapeutic goal

摘要: Clinical studies have demonstrated the benefits of thrombolytic therapy confirmed by reperfusion infarct-related arteries [1,2,3]. Early and complete patency infarct related is an important therapeutic goal during early hours after onset acute myocardial infarction (AMI). Data from numerous indicate that only a minority number patients with AMI (<40%) are eligible for thrombolysis [4]. At present current indications include chest pain consistent at least 0.1 mm ST segment elevation in 2 contiguous ECG leads whom treatment can be initiated within 12 onset, provided there no contraindications to [5]. Expanded thrombolysis, however, may markedly increase risk haemorrhagic state [1,4]. While biochemical markers sensitive specific AMI, [6,7] injury do not serve as indicator therapy.

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