Sex- and estrogen-dependent regulation of a miRNA network in the healthy and hypertrophied heart

作者: Ana Maria Queirós , Claudia Eschen , Daniela Fliegner , Georgios Kararigas , Elke Dworatzek

DOI: 10.1016/J.IJCARD.2013.09.002

关键词: Pressure overloadEstrogen receptor betaGene expressionInternal medicineFibrosisEndocrinologyCardiac fibrosisEstrogenMedicineSignal transductionmicroRNA

摘要: … the effects of E2 on gene expression and myocardial function … renilla expression in the clones carrying the Rasa1 or Rasa2 … 9 week TAC mice, we expected a sex-specific expression of …

参考文章(47)
Yunhui Cheng, Ruirui Ji, Junming Yue, Jian Yang, Xiaojun Liu, He Chen, David B. Dean, Chunxiang Zhang, MicroRNAs Are Aberrantly Expressed in Hypertrophic Heart : Do They Play a Role in Cardiac Hypertrophy? American Journal of Pathology. ,vol. 170, pp. 1831- 1840 ,(2007) , 10.2353/AJPATH.2007.061170
S. Mahmoodzadeh, D. Fliegner, E. Dworatzek, Sex differences in animal models for cardiovascular diseases and the role of estrogen. Handbook of experimental pharmacology. pp. 23- 48 ,(2013) , 10.1007/978-3-642-30726-3_2
Gary Ruvkun, Brenda J. Reinhart, Frank J. Slack, Michael Basson, Amy E. Pasquinelli, Jill C. Bettinger, Ann E. Rougvie, H. Robert Horvitz, The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans Nature. ,vol. 403, pp. 901- 906 ,(2000) , 10.1038/35002607
Thomas Thum, Nelson Chau, Balkrishen Bhat, Shashi Kumar Gupta, Peter S. Linsley, Johann Bauersachs, Stefan Engelhardt, Comparison of different miR-21 inhibitor chemistries in a cardiac disease model Journal of Clinical Investigation. ,vol. 121, pp. 461- 462 ,(2011) , 10.1172/JCI45938
Henning Witt, Carola Schubert, Juliane Jaekel, Daniela Fliegner, Adam Penkalla, Klaus Tiemann, Joerg Stypmann, Stefan Roepcke, Sebastian Brokat, Shokoufeh Mahmoodzadeh, Eva Brozova, Mercy M. Davidson, Patricia Ruiz Noppinger, Christian Grohé, Vera Regitz-Zagrosek, Sex-specific pathways in early cardiac response to pressure overload in mice. Journal of Molecular Medicine. ,vol. 86, pp. 1013- 1024 ,(2008) , 10.1007/S00109-008-0385-4
Baofeng Yang, Huixian Lin, Jiening Xiao, Yanjie Lu, Xiaobin Luo, Baoxin Li, Ying Zhang, Chaoqian Xu, Yunlong Bai, Huizhen Wang, Guohao Chen, Zhiguo Wang, The muscle-specific microRNA miR-1 regulates cardiac arrhythmogenic potential by targeting GJA1 and KCNJ2. Nature Medicine. ,vol. 13, pp. 486- 491 ,(2011) , 10.1038/NM1569
G. Petrov, V. Regitz-Zagrosek, E. Lehmkuhl, T. Krabatsch, A. Dunkel, M. Dandel, E. Dworatzek, S. Mahmoodzadeh, C. Schubert, E. Becher, H. Hampl, R. Hetzer, Regression of Myocardial Hypertrophy After Aortic Valve Replacement: Faster in Women? Circulation. ,vol. 122, ,(2010) , 10.1161/CIRCULATIONAHA.109.927764
W. C. Claycomb, N. A. Lanson, B. S. Stallworth, D. B. Egeland, J. B. Delcarpio, A. Bahinski, N. J. Izzo, HL-1 cells: A cardiac muscle cell line that contracts and retains phenotypic characteristics of the adult cardiomyocyte Proceedings of the National Academy of Sciences of the United States of America. ,vol. 95, pp. 2979- 2984 ,(1998) , 10.1073/PNAS.95.6.2979
Danish Sayed, Chull Hong, Ieng-Yi Chen, Jacqueline Lypowy, Maha Abdellatif, MicroRNAs Play an Essential Role in the Development of Cardiac Hypertrophy Circulation Research. ,vol. 100, pp. 416- 424 ,(2007) , 10.1161/01.RES.0000257913.42552.23
Edward E. Morrisey, The magic and mystery of miR-21. Journal of Clinical Investigation. ,vol. 120, pp. 3817- 3819 ,(2010) , 10.1172/JCI44596