Pressure Effects on the Reactions of Heme Proteins

作者: Karel Heremans

DOI: 10.1007/978-94-009-3827-4_18

关键词: StereochemistryChemistryMonomerSteric effectsSpin transitionHemeproteinCytochrome cMetmyoglobinImidazoleConformational change

摘要: A short review is given of the effects pressure on proteins that are relevant for studies monomeric heme proteins. The coupling spin equilibria and ligand binding processes discussed metmyoglobin. difference between horse sperm whale metmyoglobin points to steric control protein process. For imidazole a in compressibility observed high-spin low-spin compound. In final section conformational change cytochrome c at alkaline pH discussed.

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