Computational Tools for Parsimony Phylogenetic Analysis of Omics Data

作者: Jose Salazar , Hakima Amri , David Noursi , Mones Abu-Asab

DOI: 10.1089/OMI.2015.0018

关键词: DNA sequencingPhylogenetic treeProteomicsComputational biologyOmics dataDatasets as TopicOmicsBiologyGenomicsCladogramData mining

摘要: Abstract High-throughput assays from genomics, proteomics, metabolomics, and next generation sequencing produce massive omics datasets that are challenging to analyze in biological or clinical contexts. Thus far, there is no publicly available program for converting quantitative data into input formats be used off-the-shelf robust phylogenetic programs. To the best of our knowledge, this first report on creation two Windows-based programs, OmicsTract SynpExtractor, address gap. We note, as a way introduction development these one particularly useful bioinformatics inferential modeling cladogram. Cladograms multidimensional tools show relatedness between subgroups healthy diseased individuals latter's shared aberrations; they also reveal some characteristics disease would not otherwise apparent by other analytical methods. The SynpExtractor were written respective t...

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