Clinical investigation of the effect of calcium hydroxide intracanal dressing on bacterial lipopolysaccharide reduction from infected root canals
作者： Alireza Adl , Mohammad Motamedifar , Mahdi Sedigh Shams , Ahmad Mirzaie
DOI: 10.1111/AEJ.12054
关键词: Calcium hydroxide 、 Clinical investigation 、 Dentistry 、 Lipopolysaccharide 、 Pulp (tooth) 、 Materials science 、 Root canal 、 Periapical periodontitis 、 Periodontitis 、 Dental Pulp Cavity 、 General Dentistry
摘要: The purpose of this clinical study was to determine the effect 7 day intracanal dressing with calcium hydroxide on amount bacterial lipopolysaccharide (LPS; endotoxin) in human teeth necrotic and infected pulp apical periodontitis. Twenty-five single-rooted pulps periodontitis were selected. Samples collected before (S1), after root canal preparation (S2) (S3). limulus amoebocyte lysate assay used quantify LPS. LPS present 100% canals A significant reduction, equal 29.54%, found (P < 0.05). difference (equal 25.26% reduction) also detected between S2 S3 Total endotoxin reduction (S3 compared S1) be 47.34%. Endotoxin concentration reduced days hydroxide; however, relatively high values remained canals.
sci-hub.se 参考文章(34)
G. Sundqvist, Ecology of the root canal flora Journal of Endodontics. ,vol. 18, pp. 427- 430 ,(1992) , 10.1016/S0099-2399(06)80842-3
M. E. Vianna, H.-P. Horz, G. Conrads, A. A. Zaia, F. J. Souza-Filho, B. P. F. A. Gomes, Effect of root canal procedures on endotoxins and endodontic pathogens Oral Microbiology and Immunology. ,vol. 22, pp. 411- 418 ,(2007) , 10.1111/J.1399-302X.2007.00379.X
S. Assed, I.Y. Ito, M.R. Leonardo, L.A.B. Silva, D.E. Lopatin, Anaerobic microorganisms in root canals of human teeth with chronic apical periodontitis detected by indirect immunofluorescence. Endodontics & Dental Traumatology. ,vol. 12, pp. 66- 69 ,(1996) , 10.1111/J.1600-9657.1996.TB00099.X
Brenda PFA Gomes, Frederico C Martinho, Morgana E Vianna, None, Comparison of 2.5% sodium hypochlorite and 2% chlorhexidine gel on oral bacterial lipopolysaccharide reduction from primarily infected root canals. Journal of Endodontics. ,vol. 35, pp. 1350- 1353 ,(2009) , 10.1016/J.JOEN.2009.06.011
Thomas G. Dwyer, Mahmoud Torabinejad, Radiographic and histologic evaluation of the effect of endotoxin on the periapical tissues of the cat Journal of Endodontics. ,vol. 7, pp. 31- 35 ,(1981) , 10.1016/S0099-2399(81)80265-8
K SAFAVI, F NICHOLS, Effect of calcium hydroxide on bacterial lipopolysaccharide Journal of Endodontics. ,vol. 19, pp. 76- 78 ,(1993) , 10.1016/S0099-2399(06)81199-4
J. Craig Baumgartner, William A. Falkler, Bacteria in the apical 5 mm of infected root canals Journal of Endodontics. ,vol. 17, pp. 380- 383 ,(1991) , 10.1016/S0099-2399(06)81989-8
Naoki Horiba, Yoshinori Maekawa, Toru Matsumoto, Hiroshi Nakamura, A study of the distribution of endotoxin in the dentinal wall of infected root canals. Journal of Endodontics. ,vol. 16, pp. 331- 334 ,(1990) , 10.1016/S0099-2399(06)81944-8
G. Dahlén, B.C. Magnusson, Å. Möller, Histological and histochemical study of the influence of lipopolysaccharide extracted from Fusobacterium nucleatum on the periapical tissues in the monkey Macaca fascicularis Archives of Oral Biology. ,vol. 26, pp. 591- 598 ,(1981) , 10.1016/0003-9969(81)90021-2
C. R. BARTHEL, L. G. LEVIN, H. M. REISNER, M. TROPE, TNF‐α release in monocytes after exposure to calcium hydroxide treated Escherichia coli LPS International Endodontic Journal. ,vol. 30, pp. 155- 159 ,(1997) , 10.1046/J.1365-2591.1997.00066.X