Use of antibodies to carcinoembryonic antigen and human milk fat globule to distinguish carcinoma, mesothelioma, and reactive mesothelium.

作者: R J Marshall , A Herbert , S G Braye , D B Jones

DOI: 10.1136/JCP.37.11.1215

关键词: MesotheliumCarcinomaEpitheliumImmunoperoxidasePathologyChemistryMesotheliomaAdenocarcinomaPleural NeoplasmCarcinoembryonic antigen

摘要: Antibodies raised against human milk fat globule (HMFG 1 and 2) carcinoembryonic antigen were used in an immunoperoxidase technique to differentiate mesothelioma, carcinoma, benign, reactive mesothelium. Sixteen mesotheliomas, 27 lung carcinomas, 13 specimens of mesothelium examined. Staining for was not seen or mesothelioma but present 22 carcinomas. Mesothelioma carcinoma usually stained with HMFG 2; did not. These three antibodies may help distinguish

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