Absence of carcinoembryonic antigen-like material in mesotheliomaAn immunohistochemical differentiation from other lung cancers

作者: Nai-San Wang , Shao-Nan Huang , Phil Gold

DOI: 10.1002/1097-0142(197909)44:3<937::AID-CNCR2820440322>3.0.CO;2-K

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摘要: This study is to examine the potential usefulness of immunohistochemical staining for carcinoembryonic antigen (CEA)-like material in differential diagnosis mesotheliomas (12 cases) from other lung cancers (14 that had been previously diagnosed by transmission and scanning electron microscopy conventional light microscopy. Indirect immunofluorescent CEA was carried out on formalin-fixed paraffin-embedded sections, slides were examined under code. All 9 cases diffuse mesothelioma negative, all 12 adenocarcinoma bronchioloalveolar carcinoma positive CEA-like material. Three localized a carcinoid tumor also negative. A squamous cell positive. result will raise possibility its being bronchial epithelial origin.

参考文章(19)
Y Suzuki, M Kannerstein, Ultrastructure of human malignant diffuse mesothelioma. American Journal of Pathology. ,vol. 85, pp. 241- 262 ,(1976)
Nai-San Wang, Thomas A. Seemayer, M. Nisar Ahmed, Juergen Knaack, Giant cell carcinoma of the lung Human Pathology. ,vol. 7, pp. 3- 16 ,(1976) , 10.1016/S0046-8177(76)80003-2
Minassian H, Huang Sn, More Jd, Application of immunofluorescent staining on paraffin sections improved by trypsin digestion. Laboratory Investigation. ,vol. 35, pp. 383- ,(1976)
Phil Gold, Samuel O. Freedman, DEMONSTRATION OF TUMOR-SPECIFIC ANTIGENS IN HUMAN COLONIC CARCINOMATA BY IMMUNOLOGICAL TOLERANCE AND ABSORPTION TECHNIQUES Journal of Experimental Medicine. ,vol. 121, pp. 439- 462 ,(1965) , 10.1084/JEM.121.3.439
J. C. Wagner, D. E. Munday, J. S. Harington, Histochemical demonstration of hyaluronic acid in pleural mesotheliomas The Journal of Pathology and Bacteriology. ,vol. 84, pp. 73- 78 ,(1962) , 10.1002/PATH.1700840109
Phil Gold, Samuel O. Freedman, SPECIFIC CARCINOEMBRYONIC ANTIGENS OF THE HUMAN DIGESTIVE SYSTEM Journal of Experimental Medicine. ,vol. 122, pp. 467- 481 ,(1965) , 10.1084/JEM.122.3.467
J. Churg, S. H. Rosen, S. Moolten, HISTOLOGICAL CHARACTERISTICS OF MESOTHELIOMA ASSOCIATED WITH ASBESTOS Annals of the New York Academy of Sciences. ,vol. 132, pp. 614- 622 ,(1965) , 10.1111/J.1749-6632.1965.TB41141.X