A Method to Localize Occult Infections

摘要: C ommonly, in the care of critically ill patient, localization and anatomic delineation an occult infectious or inflammatory focus is essential to direct further therapeutic management. An can be considered when usual imaging modalities (including conventional radiography, computed tomography, ultrasonography) have failed delineate site extent process. Although these cases, “inflammation scanning” using Ga-citrate “In-labeled leukocytes has occasionally been useful, more often techniques had very limited clinical utility. In 1988, Fischman et al’ described a method localize focal sites infection inflammation human immunoglobulin (Ig) coupled “In with chelating agent diethylenetriamine pontaacetic acid (DTPA). Using this method, Rubin a12 1989 findings 128 patients thought infections indications for study shown Table 1. 51 patients, “In..labeled IgC correlated abdominal pelvic (21 patients), intravascular (11 pulmonary (7), skeletal (12) (Table 2). No IgG was