Muscle ring finger 1 and muscle ring finger 2 are necessary but functionally redundant during developmental cardiac growth and regulate E2F1-mediated gene expression in vivo.
作者： Monte S. Willis , Kristine M. Wadosky , Jessica E. Rodríguez , Jonathan C. Schisler , Pamela Lockyer
DOI: 10.1002/CBF.2969
关键词: Ubiquitin ligase 、 Cell biology 、 Muscle ring finger 、 Cardiac hypertrophy 、 In vivo 、 Biology 、 Molecular biology 、 Sarcomere 、 Gene expression 、 E2F 、 E2F1
摘要: Aims Muscle ring finger (MuRF) proteins have been implicated in the transmission of mechanical forces to nuclear cell signaling pathways through their association with sarcomere. We recently reported that MuRF1, but not MurF2, regulates pathologic cardiac hypertrophy vivo. This was surprising given MuRF1 and MuRF2 interact each other many same sarcomeric experimentally.
sci-hub.se 参考文章(39)
Xiao-Rui He, Chunlian Zhang, Cam Patterson, Universal mouse reference RNA derived from neonatal mice BioTechniques. ,vol. 37, pp. 464- 468 ,(2004) , 10.2144/04373RT02
D. J. O'Connor, E. W. Lam, S. Griffin, S. Zhong, L. C. Leighton, S. A. Burbidge, X. Lu, Physical and functional interactions between p53 and cell cycle co-operating transcription factors, E2F1 and DP1. The EMBO Journal. ,vol. 14, pp. 6184- 6192 ,(1995) , 10.1002/J.1460-2075.1995.TB00309.X
Alvis Brazma, Pascal Hingamp, John Quackenbush, Gavin Sherlock, Paul Spellman, Chris Stoeckert, John Aach, Wilhelm Ansorge, Catherine A. Ball, Helen C. Causton, Terry Gaasterland, Patrick Glenisson, Frank C.P. Holstege, Irene F. Kim, Victor Markowitz, John C. Matese, Helen Parkinson, Alan Robinson, Ugis Sarkans, Steffen Schulze-Kremer, Jason Stewart, Ronald Taylor, Jaak Vilo, Martin Vingron, Minimum information about a microarray experiment (MIAME)-toward standards for microarray data. Nature Genetics. ,vol. 29, pp. 365- 371 ,(2001) , 10.1038/NG1201-365
Tomohiko Ohta, Yue Xiong, Phosphorylation- and SKP1-independent in Vitro ubiquitination of E2F1 by multiple ROC-cullin ligases Cancer Research. ,vol. 61, pp. 1347- 1353 ,(2001)
G Eelen, I Vanden Bempt, L Verlinden, M Drijkoningen, A Smeets, P Neven, M R Christiaens, K Marchal, R Bouillon, A Verstuyf, Expression of the BRCA1-interacting protein Brip1 / BACH1/FANCJ is driven by E2F and correlates with human breast cancer malignancy Oncogene. ,vol. 27, pp. 4233- 4241 ,(2008) , 10.1038/ONC.2008.51
Henning Ebelt, Zhipei Liu, Ursula Müller-Werdan, Karl Werdan, Thomas Braun, Making omelets without breaking eggs: E2F-mediated induction of cardiomyoycte cell proliferation without stimulation of apoptosis. Cell Cycle. ,vol. 5, pp. 2436- 2439 ,(2006) , 10.4161/CC.5.21.3402
Jörg J Jacoby, April Kalinowski, Mu-Gen Liu, Samuel S-M Zhang, Qian Gao, Gui-Xuan Chai, Lan Ji, Yoshiki Iwamoto, En Li, Michael Schneider, Kerry S Russell, Xin-Yuan Fu, Cardiomyocyte-restricted knockout of STAT3 results in higher sensitivity to inflammation, cardiac fibrosis, and heart failure with advanced age Proceedings of the National Academy of Sciences of the United States of America. ,vol. 100, pp. 12929- 12934 ,(2003) , 10.1073/PNAS.2134694100
V. Kedar, H. McDonough, R. Arya, H.-H. Li, H. A. Rockman, C. Patterson, Muscle-specific RING finger 1 is a bona fide ubiquitin ligase that degrades cardiac troponin I Proceedings of the National Academy of Sciences of the United States of America. ,vol. 101, pp. 18135- 18140 ,(2004) , 10.1073/PNAS.0404341102
R Agah, L A Kirshenbaum, M Abdellatif, L D Truong, S Chakraborty, L H Michael, M D Schneider, Adenoviral delivery of E2F-1 directs cell cycle reentry and p53-independent apoptosis in postmitotic adult myocardium in vivo. Journal of Clinical Investigation. ,vol. 100, pp. 2722- 2728 ,(1997) , 10.1172/JCI119817
Stephanie H. Witt, Henk Granzier, Christian C. Witt, Siegfried Labeit, MURF-1 and MURF-2 target a specific subset of myofibrillar proteins redundantly: towards understanding MURF-dependent muscle ubiquitination. Journal of Molecular Biology. ,vol. 350, pp. 713- 722 ,(2005) , 10.1016/J.JMB.2005.05.021