Thyroid failure in the elderly: microsomal antibodies as discriminant for therapy

作者: Mark J Rosenthal , William C Hunt , Philip J Garry , James S Goodwin

DOI: 10.1001/JAMA.1987.03400020051029

关键词: MicrosomeAntibodyRadioimmunoassayEndocrinologyHormoneMedicineTriiodothyronineThyroidEndocrine glandPeptide hormoneInternal medicine

摘要: Thyrotropin (thyroid-stimulating hormone [TSH]) levels were elevated above 4.0 mU/L (μU/mL) in serum samples from 13.2% of 258 healthy elderly subjects. To investigate the natural history progressive thyroid failure, serial functions measured for four years 26 these subjects with TSH levels. In one third subjects, biochemical failure developed (thyroxine level ( JAMA 1987;258:209-213)

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