作者: V. I. Reus , N. Freimer
DOI: 10.1007/978-3-642-74034-3_36
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摘要: A variety of disturbances in thyroid regulation, ranging nature from subtle to overt, have been reported patients with primary psychiatric diagnoses (Loosen 1986; Zach and Ackerman 1988). The continuing dilemma interpretation these findings centers on whether they represent isolated unrelated hormonal regulation or are rather varying functional presentations an underlying central defect a significant percentage the population under study. key advance this regard has recognition recent years that majority abnormalities evolve genetically transmitted alteration immune (Weetman McGregor 1984). development autoimmune disease is complex progressive process, most likely involving organic specific suppressor T-lymphocytes, aberrant expression HLA antigens membranes cells, one more environmental precipitating stimuli, addition genetic factors already mentioned. Abnormalities metabolism function relatively late sequelae pathologic change events.