Emerging regulators of the inflammatory process in osteoarthritis

作者: Ru Liu-Bryan , Robert Terkeltaub

DOI: 10.1038/NRRHEUM.2014.162

关键词: Unfolded protein responseProteostasisAMPKMedicineInflammationCell biologyProinflammatory cytokineAutophagyReprogrammingImmunologyProtein kinase A

摘要: … metal regulatory transcriptional factor 1 (MTF1), have been reported … Evidently, the HIF-2α and MTF1 transcriptional regulatory … The ZIP8-mediated and MTF1 pathway mechanism would …

参考文章(111)
Beatriz Caramés, William B. Kiosses, Yukio Akasaki, Diana C. Brinson, William Eap, James Koziol, Martin K. Lotz, Glucosamine Activates Autophagy In Vitro and In Vivo Arthritis & Rheumatism. ,vol. 65, pp. 1843- 1852 ,(2013) , 10.1002/ART.37977
Denise L. Cecil, C. Thomas G. Appleton, Monika D. Polewski, John S. Mort, Ann Marie Schmidt, Alison Bendele, Frank Beier, Robert Terkeltaub, The Pattern Recognition Receptor CD36 Is a Chondrocyte Hypertrophy Marker Associated with Suppression of Catabolic Responses and Promotion of Repair Responses to Inflammatory Stimuli Journal of Immunology. ,vol. 182, pp. 5024- 5031 ,(2009) , 10.4049/JIMMUNOL.0803603
Koji Takada, Jun Hirose, Kei Senba, Soichiro Yamabe, Yuichi Oike, Tomomi Gotoh, Hiroshi Mizuta, Enhanced apoptotic and reduced protective response in chondrocytes following endoplasmic reticulum stress in osteoarthritic cartilage. International Journal of Experimental Pathology. ,vol. 92, pp. 232- 242 ,(2011) , 10.1111/J.1365-2613.2010.00758.X
Christopher L Murphy, HIF-2alpha--a mediator of osteoarthritis? Cell Research. ,vol. 20, pp. 977- 979 ,(2010) , 10.1038/CR.2010.99
Cécile Lambert, Jean‐Emile Dubuc, Eulàlia Montell, Josep Vergés, Carine Munaut, Agnès Noël, Yves Henrotin, Gene expression pattern of cells from inflamed and normal areas of osteoarthritis synovial membrane Arthritis & Rheumatism. ,vol. 66, pp. 960- 968 ,(2014) , 10.1002/ART.38315
Mary B Goldring, Steven R Goldring, None, Articular cartilage and subchondral bone in the pathogenesis of osteoarthritis Annals of the New York Academy of Sciences. ,vol. 1192, pp. 230- 237 ,(2010) , 10.1111/J.1749-6632.2009.05240.X
Christin M. Lepus, Jason J. Song, Qian Wang, Catriona A. Wagner, Tamsin M. Lindstrom, Constance R. Chu, Jeremy Sokolove, Lawrence L. Leung, William H. Robinson, Brief report: carboxypeptidase B serves as a protective mediator in osteoarthritis. Arthritis & Rheumatism. ,vol. 66, pp. 101- 106 ,(2014) , 10.1002/ART.38213
Richard F. Loeser, Steven R. Goldring, Carla R. Scanzello, Mary B. Goldring, Osteoarthritis: A disease of the joint as an organ Arthritis & Rheumatism. ,vol. 64, pp. 1697- 1707 ,(2012) , 10.1002/ART.34453
Ru Liu-Bryan, Robert Terkeltaub, The growing array of innate inflammatory ignition switches in osteoarthritis. Arthritis & Rheumatism. ,vol. 64, pp. 2055- 2058 ,(2012) , 10.1002/ART.34492