Epigenetics of articular cartilage in knee and hip OA

作者: John Loughlin , Louise N. Reynard

DOI: 10.1038/NRRHEUM.2014.189

关键词: Complex diseaseArticular cartilageMedicineDNA methylationPhysical therapyEpigeneticsBioinformaticsCartilageHuman diseaseOsteoarthritis

摘要: Epigenetic regulation is a vital driver of the aetiology human disease, with research breakthroughs now occurring on regular basis. Several studies investigating CpG methylation cartilage DNA from patients osteoarthritis are generating exciting insight into this common but complex disease.

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