Detecting early functional damage in glaucoma suspect and ocular hypertensive patients with the multifocal VEP technique.

摘要: PURPOSE: To determine whether the multifocal visual evoked potential (mfVEP) technique can detect early functional damage in ocular hypertensive (OHT) and glaucoma suspect (GS) patients with normal standard achromatic automated perimetry (SAP) results. PATIENTS AND METHODS: Twenty-five GS (25 eyes), 25 OHT 50 controls (50 eyes) were enrolled this study. All GS, control eyes had SAP as defined by a pattern deviation mean within 95% confidence interval hemifield test limits on Humphrey field 24-2 program. Eyes optic disc changes consistent or without raised intraocular pressure (IOP), showed no evidence of glaucomatous neuropathy IOPs >or=22 mm Hg. Monocular mfVEPs obtained from both each subject using pattern-reversal dartboard array 60 sectors. The entire display radius 22.3 degrees. mfVEPs, for eye, abnormal when either monocular interocular probability plot cluster 3 more contiguous points P<0.05 at least 2 these P<0.01. RESULTS: mfVEP results 4% subjects. Abnormal detected 20% 16% patients. Significantly abnormalities than controls. However, there was significant difference between CONCLUSIONS: deficits minority disks