Bayesian Adaptive Designs in Phase I/II Clinical Trials

作者: Wei Zhong

DOI:

关键词: GerontologyComputer fileBayesian probabilityMedicineBiostatisticsMedical physicsPhase i iiClinical trial

摘要: University of Minnesota Ph.D. dissertation. September 2012. Major: Biostatistics. Advisors:Bradley P. Carlin, Joseph S. Koopmeiners. 1 computer file (PDF); xi, 80 pages.

参考文章(51)
T. Pham-Gia, N. Turkkan, Sample Size Determination in Bayesian Analysis The Statistician. ,vol. 41, pp. 389- 397 ,(1992) , 10.2307/2349003
Thomas M. Braun, The bivariate continual reassessment method Controlled Clinical Trials. ,vol. 23, pp. 240- 256 ,(2002) , 10.1016/S0197-2456(01)00205-7
Bradley P. Carlin, Scott M. Berry, Peter Muller, J. Jack Lee, Bayesian Adaptive Methods for Clinical Trials ,(2010)
Bruce W. Turnbull, Christopher Jennison, Group Sequential Methods with Applications to Clinical Trials ,(1999)
Marvin Zelen, Sandra J. Lee, Clinical Trials and Sample Size Considerations: Another Perspective Statistical Science. ,vol. 15, pp. 95- 110 ,(2000) , 10.1214/SS/1009212752
Donald A Berry, Peter Mueller, Andy P Grieve, Michael Smith, Tom Parke, Richard Blazek, Neil Mitchard, Michael Krams, None, Adaptive Bayesian Designs for Dose-Ranging Drug Trials Case Studies in Bayesian Statistics Volume V. pp. 99- 181 ,(2002) , 10.1007/978-1-4613-0035-9_2
Sumithra J. Mandrekar, Rui Qin, Daniel J. Sargent, Model‐based phase I designs incorporating toxicity and efficacy for single and dual agent drug combinations: Methods and challenges Statistics in Medicine. ,vol. 29, pp. 1077- 1083 ,(2010) , 10.1002/SIM.3706
D. J. Spiegelhalter, L. S. Freedman, A predictive approach to selecting the size of a clinical trial, based on subjective clinical opinion Statistics in Medicine. ,vol. 5, pp. 1- 13 ,(1986) , 10.1002/SIM.4780050103
Shara Yurkiewicz, The Prospects for Personalized Medicine Hastings Center Report. ,vol. 40, pp. 14- 16 ,(2010) , 10.1353/HCR.2010.0002