作者: Michael G. Hart , Stephen J. Price , John Suckling
关键词: Resting state fMRI 、 Neuroscience 、 Magnetic resonance imaging 、 Default mode network 、 Temporal lobe 、 Brain mapping 、 Stimulus (physiology) 、 Nerve net 、 Neurosurgery 、 Medicine
摘要: OBJECTIVEResection of focal brain lesions involves maximizing the resection while preserving function. Mapping function has entered a new era focusing on distributed connectivity networks at “rest,” that is, in absence specific task or stimulus, requiring minimal participant engagement. Central to this frame shift been development methods for rapid assessment whole-brain with functional MRI (fMRI) involving blood oxygenation level–dependent imaging. The authors appraised feasibility fMRI-based mapping repertoire neurosurgical patients and potential benefits resting-state surgical planning.METHODSResting-state fMRI sequences 3-T scanner multiecho echo-planar imaging coupled independent component analysis were acquired preoperatively from 5 study participants who had right temporoparietooccipital glioblastoma. Seed-based connecti...