作者: Suzane Lucas Schechtel , Vanessa Cristina Rodrigues Matos , Jânio Sousa Santos , Thiago Mendanha Cruz , Mariza Boscacci Marques
关键词: Ellagic acid 、 Composition (visual arts) 、 Procyanidin A2 、 IC50 、 Food science 、 Lipid oxidation 、 Chemistry 、 Antioxidant 、 Bioassay 、 Human nutrition
摘要: This work aimed to investigate the phytochemical composition, nutritional value, antioxidant, antihemolytic, antihyperglycemic, and antiproliferative activities of flaxleaf fleabane (Conyza bonariensis) leaves. Different concentrations water ethanol (0:100, 25:75, 50:50, 75:25, 100:0 v/v) were used in extraction process results showed that hydroalcoholic extract (50:50 presented highest total phenolics, ortho-diphenolics, Folin-Ciocalteu reducing capacity, FRAP, Fe2+ chelating ability values. Flaxleaf leaves (FFL) contained 19.6 g/100 g fibers 26 proteins. Ellagic acid, procyanidin A2, caffeic, rosmarinic, gallic, 2,5-dihydroxybenzoic acids main phenolics. phenolic-rich inhibited lipid oxidation Wistar rat brain (IC50 = 863.0 mg GAE/L), α-glucosidase activity 435.4 µg/mL), protected human erythrocytes against mechanical hemolysis at different osmolarity conditions, cytotoxic/antiproliferative effects ileocecal adenocarcinoma cells (HCT8; IC50 552.6 µg/mL) but no cytotoxicity toward noncancerous lung fibroblast (IMR90). Overall, FFL potential be explored by food companies a source proteins, natural color substances, phenolic compounds. PRACTICAL APPLICATION: are usually burnt or partially given cattle, without proper utilization as nutrients for nutrition. Here, we studied toxicological aspects using biological protocols. was proven rich proteins dietary antioxidant measured chemical vitro assays. Additionally, it did red not show cytotoxicity, assume has relative safety consumed nonconventional edible plant.