作者: Wilfrid Rall
DOI: 10.1016/0014-4886(59)90046-9
关键词: Neuroscience 、 Axonal membrane 、 Neuron 、 Classical theory 、 Conductance 、 Biology 、 Branching (linguistics) 、 Soma 、 Membrane resistivity 、 Intracellular microelectrodes
摘要: Abstract This paper is concerned with both the quantitative information and theory required for interpretation of certain experimental results obtained intracellular microelectrodes. The treats spread current from a neuron soma into branching dendritic trees. Formulas are derived calculation membrane resistivity physiological measurements whole resistance anatomical dimensions. variability available discussed. numerical result an estimated range values mammalian motoneurons, corresponding set to conductance ratio. These significantly greater than those currently accepted in literature, mainly because dimensions appear have been underestimated previously. Analysis histological evidence also reveals significant differences between infant, adult, chromatolytic motoneurons. builds upon classical axonal electrotonus; all important assumptions explicitly stated general can be applied many types neurons trees; it relevant diffusion material neurons. 3 2 power trunk diameter shown fundamental index size. Another parameter characterizes extensiveness branching.