Branching dendritic trees and motoneuron membrane resistivity.

作者: Wilfrid Rall

DOI: 10.1016/0014-4886(59)90046-9

关键词: NeuroscienceAxonal membraneNeuronClassical theoryConductanceBiologyBranching (linguistics)SomaMembrane resistivityIntracellular microelectrodes

摘要: Abstract This paper is concerned with both the quantitative information and theory required for interpretation of certain experimental results obtained intracellular microelectrodes. The treats spread current from a neuron soma into branching dendritic trees. Formulas are derived calculation membrane resistivity physiological measurements whole resistance anatomical dimensions. variability available discussed. numerical result an estimated range values mammalian motoneurons, corresponding set to conductance ratio. These significantly greater than those currently accepted in literature, mainly because dimensions appear have been underestimated previously. Analysis histological evidence also reveals significant differences between infant, adult, chromatolytic motoneurons. builds upon classical axonal electrotonus; all important assumptions explicitly stated general can be applied many types neurons trees; it relevant diffusion material neurons. 3 2 power trunk diameter shown fundamental index size. Another parameter characterizes extensiveness branching.

参考文章(29)
William Frederick Windle, Biology of neuroglia C.C. Thomas. ,(1958)
The electrical constants of a crustacean nerve fibre. Proceedings of The Royal Society B: Biological Sciences. ,vol. 133, pp. 444- 479 ,(1946) , 10.1098/RSPB.1946.0024
J. S. COOMBS, D. R. CURTIS, J. C. ECCLES, Time courses of motoneuronal responses. Nature. ,vol. 178, pp. 1049- 1050 ,(1956) , 10.1038/1781049A0
Liang-Wei Chu, A cytological study of anterior horn cells isolated from human spinal cord The Journal of Comparative Neurology. ,vol. 100, pp. 381- 413 ,(1954) , 10.1002/CNE.901000206
J. S. Coombs, D. R. Curtis, J. C. Eccles, The electrical constants of the motoneurone membrane The Journal of Physiology. ,vol. 145, pp. 505- 528 ,(1959) , 10.1113/JPHYSIOL.1959.SP006158
Robert A. Haggar, Murray L. Barr, Quantitative data on the size of synaptic end‐bulbs in the cat's spinal cord. With a note on the preparation of cell models The Journal of Comparative Neurology. ,vol. 93, pp. 17- 35 ,(1950) , 10.1002/CNE.900930103
W. RALL, Membrane time constant of motoneurons. Science. ,vol. 126, pp. 454- 454 ,(1957) , 10.1126/SCIENCE.126.3271.454
Karl Balthasar, [Morphology of the spinal tibialis-and peroneus nuclei in the cat: topography, architecture, course of axons and dendrites of the motoric neurons and the intermediate neurons in the segments L6-S2]. Archiv für Psychiatrie und Nervenkrankheiten, vereinigt mit Zeitschrift für die gesamte Neurologie und Psychiatrie. ,vol. 188, pp. 345- 378 ,(1952) , 10.1007/BF00367982
Wilfrid Rall, Membrane potential transients and membrane time constant of motoneurons. Experimental Neurology. ,vol. 2, pp. 503- 532 ,(1960) , 10.1016/0014-4886(60)90029-7