Can adipokines serum levels be used as biomarkers of hand osteoarthritis

作者: A. Fioravanti , S. Cheleschi , A. De Palma , O. Addimanda , L. Mancarella

DOI: 10.1080/1354750X.2017.1401665

关键词: Hand osteoarthritisResistinAdipokineInternal medicineOsteoarthritisGastroenterologyAdiponectinIn patientCase-control studyNicotinamide phosphoribosyltransferaseMedicine

摘要: AbstractPurpose: To evaluate serum levels of visfatin, resistin and adiponectin in patients with erosive (E) non-erosive (NE) osteoarthritis (OA) the hand (HOA) compared to normal controls (NC).Methods: 94 outpatients E HOA NE 21 NC were enrolled. The radiological assessment both hands was performed according Kellgren–Lawrence Kallman score. Patients divided into two subsets (lone or generalized OA) based on clinically OA involvement knee hip. Serum determined by ELISA assay.Results: Visfatin significantly higher comparison group. Resistin showed a significant increase groups versus NC, particular OA. No differences among found adiponectin. score more severe HOA.Conclusions: This study increased erosi...

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