Autologous transplant for primary mediastinal B-cell lymphoma

作者: Xavier Poiré , Koen van Besien

DOI: 10.1586/17474086.2.1.31

关键词: Primary mediastinal B-cell lymphomaRadiation therapyRituximabLymphomaInternal medicineChemotherapySurgeryOncologyAutologous stem-cell transplantationStem cellLarge-cell lymphomaMedicine

摘要: Evaluation of: Rodriguez J, Conde E, Gutierrez A et al. Primary mediastinal large cell lymphoma (PMBCL) frontline treatment with autologous stem transplantation (ASCT). The GEL-TAMO experience. Hematol. Oncol. 26, 171–178 (2008).Primary B-cell is a subtype of that shares similarities diffuse and classic Hodgkin’s lymphoma. current study evaluates the use transplant (ASCT) as part initial therapy in cohort patients PMBCL treated between 1985 2006. demonstrates excellent survival progression-free for complete remission (CR) at ASCT, those achieving CR after ASCT. It also shows benefit to administration involved-field radiation therapy. However, front-line has evolved considerably since these were treated. Dose-dense chemotherapy regimens show results without incorporation rituximab the...

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